The tribulation will bring the greatest time of trouble ever to come upon mankind. According to Bible prophecy, it will occur during “the last days,” or “the end time.” (2 Timothy 3:1; Daniel 12:4, New American Bible) It will be “a tribulation such as has not occurred from the beginning of the creation that God created until that time, and will not occur again.”​—Mark 13:19; Daniel 12:1; Matthew 24:21, 22.