Stem cells engineered using genome editing technology

International Business Times – Jayalakshmi K

dna-double-helixIn a first, the Johns Hopkins team used the techniques to modify and tailor human-induced pluripotent stem cells (iPSCs). The genome editing method uses an enzyme that pins together DNA with a piece of small RNA that guides the tool to where researchers want to introduce changes in the genome. While CRISPR has been known to generate genomic changes far more efficiently than other gene editing techniques, there have been fears of it leading to unintended changes on off-target genes. Gene drives that select some genes and even include some man-made ones, driving particular traits to spread through a species, could present environmental and security challenges warned experts. Read Full article



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